SMC3 antibody (AA 1010-1090)

Catalog No. ABIN8124996

The Rabbit Polyclonal anti-SMC3 antibody is suitable to detect SMC3 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for SMC3 antibody (AA 1010-1090) (ABIN8124996)

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SMC3 Antibody

Binding Specificity: AA 1010-1090

Purpose: SMC3 Antibody

Specificity: SMC3 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human protein . at AA range: 1010-1090

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SMC3

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Alternative Name: SMC3

Background:

Background: This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008],

Gene Name: SMC3 BAM BMH CSPG6 SMC3L1

Protein Name: Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) (Basement membrane-associated chondroitin proteoglycan) (Bamacan) (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP)

Gene ID: 9126

UniProt: Q9UQE7

Pathways: Stem Cell Maintenance