SMC3 antibody (pSer1083)

Catalog No. ABIN8124997

The Rabbit Polyclonal anti-SMC3 antibody (ABIN8124997) specifically detects SMC3 in WB, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for SMC3 antibody (pSer1083) (ABIN8124997)

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-SMC3 Antibody

Binding Specificity: pSer1083

Purpose: Bamacan (Phospho Ser1083) Antibody

Specificity: This antibody detects endogenous phospho levels of Bamacan (Phospho-Ser1083) at Human:S1083, Mouse:S1083, Rat:S1083

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human Bamacan (Phospho-Ser1083)

Isotype: IgG

Application Details

Application Notes: IHC 1:50-200, WB 1:500-2000. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for SMC3

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Alternative Name: Bamacan

Background:

Synonyms: Structural maintenance of chromosomes protein 3 (SMC protein 3, SMC-3, Basement membrane-associated chondroitin proteoglycan, Bamacan, Chondroitin sulfate proteoglycan 6, Chromosome-associated polypeptide, hCAP)

Background: This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq, Jul 2008],

Gene Name: SMC3 BAM BMH CSPG6 SMC3L1

Protein Name: Bamacan (Phospho-Ser1083)

Gene ID: 9126

UniProt: Q9UQE7

Pathways: Stem Cell Maintenance