Talin antibody (pSer425)

Catalog No. ABIN8125107

The Rabbit Polyclonal anti-Talin antibody is suitable to detect Talin in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for Talin antibody (pSer425) (ABIN8125107)

Target: Talin (TLN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Talin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Talin Antibody

Binding Specificity: pSer425

Purpose: Talin (Phospho Ser425) Antibody

Specificity: This antibody detects endogenous levels of Human Mouse Rat Talin (phospho-Ser425)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human Talin (Ser425)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Talin

Target: Talin (TLN)

Alternative Name: Talin

Background:

Synonyms: Talin-1

Background: This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin. [provided by RefSeq, Feb 2009],

Gene Name: TLN1 KIAA1027 TLN

Protein Name: Talin (Ser425)

Gene ID: 7094

UniProt: Q9Y490