Thyroperoxidase antibody (AA 600-700)

Catalog No. ABIN8125210

The Rabbit Monoclonal anti-Thyroperoxidase antibody (Clone AB1439) (ABIN8125210) specifically detects Thyroperoxidase in IHC. The antibody is reactive with Human samples.

Quick Overview for Thyroperoxidase antibody (AA 600-700) (ABIN8125210)

Target: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Thyroperoxidase antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1439

Product Details anti-Thyroperoxidase Antibody

Binding Specificity: AA 600-700

Purpose: Thyroid Peroxidase (TPO) Rabbit mAb (Ready to Use)

Specificity: The antibody can recognize human Thyroid Peroxidase protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 600 - 700 of the human Thyroid Peroxidase protein.

Isotype: IgG

Application Details

Application Notes: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze

Storage: 4 °C

Storage Comment: Store at 4°C. Avoid freeze.

Target Details for Thyroperoxidase

Target: Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))

Alternative Name: Thyroid Peroxidase

Background:

Synonyms: Thyroid peroxidase,TPO,

Background: Thyroperoxidase (TPO) is an enzyme expressed mainly in the thyroid gland and directly participates in iodine oxidation, tyrosine iodization and tyrosine iodide coupling in thyroid cells. The expression of TPO is related to tissue differentiation and function of follicular cells. TPO is highly expressed in normal, proliferative and most benign tumorous thyroid tissues, and significantly decreased in malignant thyroid tumors. Therefore, the antibody can be used in differential diagnosis of benign and malignant thyroid tissue.

Gene Name: TPO

Protein Name: Thyroid Peroxidase (TPO)

Gene ID: 3662

UniProt: P07202

Pathways: Thyroid Hormone Synthesis