TFF1 antibody (AA 25-84)

Catalog No. ABIN8125374

The Mouse Monoclonal anti-TFF1 antibody is suitable to detect TFF1 in samples from Human. It has been validated for IHC.

Quick Overview for TFF1 antibody (AA 25-84) (ABIN8125374)

Target: TFF1 (Trefoil Factor 1 (TFF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TFF1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1398

Product Details anti-TFF1 Antibody

Binding Specificity: AA 25-84

Purpose: pS2 mouse mAb

Specificity: The antibody can specifically recognize human pS2 protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 25 - 84 of the human pS2 protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for TFF1

Target: TFF1 (Trefoil Factor 1 (TFF1))

Alternative Name: pS2

Background:

Synonyms: BCEI, Breast cancer estrogen inducible protein, Breast cancer estrogen inducible sequence, Breast cancer estrogen-inducible protein, D21S21, Gastrointestinal trefoil protein, Gastrointestinal trefoil protein pS2, hP1. A, HP1A, HPS 2, HPS2, pNR 2, PNR-2, pNR2, Polypeptide P1. A, Protein pS2, PS 2, pS2, pS2 protein, TFF 1, TFF1, TFF1_HUMAN, Trefoil factor 1

Background: PS2, also known as pnr-2, is a cytoplasmic polypeptide regulated by estrogen with a molecular weight of 6. 5 kDa. It is expressed in breast epithelium, normal gastric mucosa and small intestinal mucosa. It is mainly used for breast cancer and gastric cancer research. PS2 positive is more common in ER and PR positive breast cancer. It can be used for breast cancer patients to study endocrine therapy response.

Gene Name: TFF1

Protein Name: pS2

Gene ID: 7031

UniProt: P04155

Pathways: EGFR Signaling Pathway