TRIM23 antibody

Catalog No. ABIN8125387

The Rabbit Polyclonal anti-TRIM23 antibody (ABIN8125387) specifically detects TRIM23 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TRIM23 antibody (ABIN8125387)

Target: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM23 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-TRIM23 Antibody

Purpose: TRI23 Antibody

Specificity: TRI23 Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for TRIM23

Target: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Alternative Name: TRI23

Background:

Background: The protein encoded byThis gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described. [provided by RefSeq, Jul 2008],

Gene Name: TRIM23 ARD1 ARFD1 RNF46

Protein Name: E3 ubiquitin-protein ligase TRIM23 (EC 6.3.2.-) (ADP-ribosylation factor domain-containing protein 1) (GTP-binding protein ARD-1) (RING finger protein 46) (Tripartite motif-containing protein 23)

Gene ID: 373

UniProt: P36406