TYR antibody (AA 250-350)

Catalog No. ABIN8125495

The Mouse Monoclonal anti-TYR antibody (Clone AB1386) (ABIN8125495) specifically detects TYR in IHC. The antibody is reactive with Human samples.

Quick Overview for TYR antibody (AA 250-350) (ABIN8125495)

Target: TYR (Tyrosinase (TYR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TYR antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1386

Product Details anti-TYR Antibody

Binding Specificity: AA 250-350

Purpose: Tyrosinase mouse mAb

Specificity: The antibody can specifically recognize human Tyrosinase protein.

Purification: The antibody was purified by affinity chromatography using a specific immunogen.

Immunogen: A synthetic peptide corresponding to the amino acid region 250 - 350 of the human Tyrosinase protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for TYR

Target: TYR (Tyrosinase (TYR))

Alternative Name: Tyrosinase

Background:

Synonyms: ATN, CMM8, LB24 AB, LB24-AB, Monophenol monooxygenase, OCA1, OCA1A, OCAIA, Oculocutaneous albinism IA, SHEP3, SK29 AB, SK29-AB, Tumor rejection antigen AB, TYR, TYRO_HUMAN, tyrosinase (oculocutaneous albinism IA) , Tyrosinase

Background: Tyrosinase is a key member of the melanin biosynthetic enzyme family in melanocytes and a key enzyme in the initial stage of melanin biosynthesis. It is located in melanocytes, which are mainly distributed in skin, hair ball and eyes. Tyrosinase is a specific marker of melanocytes. Its deletion is associated with various albinism, especially ocular skin albinism. It is mainly used for the study of albinism and malignant melanoma.

Gene Name: TYR

Protein Name: Tyrosinase

Gene ID: 7299

UniProt: P14679