TYR antibody (AA 250-350)

Catalog No. ABIN8125496

This Mouse Monoclonal antibody specifically detects TYR in IHC, WB, IF and ELISA. It exhibits reactivity toward Human and Mouse.

Quick Overview for TYR antibody (AA 250-350) (ABIN8125496)

Target: TYR (Tyrosinase (TYR))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TYR antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), ELISA

Clone: AB1603

Product Details anti-TYR Antibody

Binding Specificity: AA 250-350

Purpose: Tyrosinase mouse mAb

Specificity: This antibody detects endogenous levels of Tyrosinase protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 250 - 350 of the human Tyrosinase protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for TYR

Target: TYR (Tyrosinase (TYR))

Alternative Name: Tyrosinase

Background:

Synonyms: ATN, CMM8, LB24 AB, LB24-AB, Monophenol monooxygenase, OCA1, OCA1A, OCAIA, Oculocutaneous albinism IA, SHEP3, SK29 AB, SK29-AB, Tumor rejection antigen AB, TYR, TYRO_HUMAN, tyrosinase (oculocutaneous albinism IA) , Tyrosinase

Background: tyrosinase (TYR) Homo sapiens The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008],

Gene Name: TYR

Protein Name: Tyrosinase

Gene ID: 7299

UniProt: P14679