UBE4A antibody

Catalog No. ABIN8125586

This Rabbit Polyclonal antibody specifically detects UBE4A in ELISA, IHC and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for UBE4A antibody (ABIN8125586)

Target: UBE4A (Ubiquitination Factor E4A (UBE4A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBE4A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-UBE4A Antibody

Purpose: UFD2 Antibody

Specificity: UFD2 Polyclonal Antibody detects endogenous levels of UFD2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human UFD2.

Isotype: IgG

Application Details

Application Notes: IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for UBE4A

Target: UBE4A (Ubiquitination Factor E4A (UBE4A))

Alternative Name: UFD2

Background:

Synonyms: UBE4B, HDNB1, KIAA0684, UFD2, Ubiquitin conjugation factor E4 B, Homozygously deleted in neuroblastoma 1, Ubiquitin fusion degradation protein 2

Background: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s.This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Gene Name: UBE4B

Protein Name: Ubiquitin conjugation factor E4 B

Gene ID: 10277

UniProt: O95155