UPB1 antibody

Catalog No. ABIN8125614

The Rabbit Monoclonal anti-UPB1 antibody is suitable to detect UPB1 in samples from Human. It has been validated for WB, IHC and IP.

Quick Overview for UPB1 antibody (ABIN8125614)

Target: UPB1 (Ureidopropionase, beta (UPB1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This UPB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: AB2247

Product Details anti-UPB1 Antibody

Purpose: UPB1 Rabbit mAb

Specificity: This antibody detects endogenous levels of UPB1 protein.

Purification: The antibody was purified by protein A affinity chromatography.

Immunogen: Recombinant protein (or fragment).

Isotype: IgG

Application Details

Application Notes: WB, 1:1000-1:5000 | IHC, 1:•100-1:300 | IP, 0. 5 μg-4 μg antibody for 200 μg-400 μg extracts of whole cells. |

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for UPB1

Target: UPB1 (Ureidopropionase, beta (UPB1))

Alternative Name: UPB1

Background:

Synonyms: UPB1, BUP1, Beta-ureidopropionase , BUP-1, Beta-alanine synthase, N-carbamoyl-beta-alanine amidohydrolase,

Background: This gene encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH) , dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity. [provided by RefSeq, Jul 2008]

Gene Name: UPB1, BUP1

Protein Name: UPB1

Gene ID: 51733

UniProt: Q9UBR1