MYB antibody (acLys480)

Catalog No. ABIN8125644

The Rabbit Polyclonal anti-MYB antibody is suitable to detect MYB in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for MYB antibody (acLys480) (ABIN8125644)

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYB antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-MYB Antibody

Binding Specificity: acLys480

Purpose: c-Myb (Acetyl Lys480) Antibody

Specificity: This antibody detects endogenous levels of Human,Mouse c-Myb (Acetyl Lys480)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized peptide derived from human c-Myb (Acetyl Lys480)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for MYB

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Alternative Name: c-Myb

Background:

Synonyms: Transcriptional activator Myb (Proto-oncogene c-Myb)

Background: domain:Comprised of 3 domains, an N-terminal DNA-binding domain, a centrally located transcriptional activation domain and a C-terminal domain involved in transcriptional repression.,function:Transcriptional activator, DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.,PTM:Phosphorylated by NLK on multiple sites, which induces proteasomal degradation.,PTM:Ubiquitinated, mediated by SIAH1 and leading to its subsequent proteasomal degradation.,similarity:Contains 3 HTH myb-type DNA-binding domains.,subunit:Binds MYBBP1A. Interacts with HIPK2, MAF and NLK.,

Gene Name: MYB

Protein Name: c-Myb (Acetyl Lys480)

Gene ID: 4602

UniProt: P10242

Pathways: Chromatin Binding, Positive Regulation of Immune Effector Process