VRK3 antibody

Catalog No. ABIN8125658

This Rabbit Polyclonal antibody specifically detects VRK3 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for VRK3 antibody (ABIN8125658)

Target: VRK3 (Vaccinia Related Kinase 3 (VRK3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VRK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-VRK3 Antibody

Purpose: VRK3 Antibody

Specificity: VRK3 Polyclonal Antibody detects endogenous levels of VRK3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human VRK3.

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for VRK3

Target: VRK3 (Vaccinia Related Kinase 3 (VRK3))

Alternative Name: VRK3

Background:

Synonyms: VRK3, Inactive serine/threonine-protein kinase VRK3, Serine/threonine-protein pseudokinase VRK3, Vaccinia-related kinase 3

Background: vaccinia related kinase 3(VRK3) Homo sapiens This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008],

Gene Name: VRK3

Protein Name: Inactive serine/threonine-protein kinase VRK3

Gene ID: 51231

UniProt: Q8IV63