VTI1B antibody

Catalog No. ABIN8125692

The Rabbit Polyclonal anti-VTI1B antibody is suitable to detect VTI1B in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for VTI1B antibody (ABIN8125692)

Target: VTI1B (Vesicle Transport through Interaction with T-SNAREs Homolog 1B (VTI1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VTI1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-VTI1B Antibody

Purpose: v-SNARE Vti1p Antibody

Specificity: V-SNARE Vti1p Polyclonal Antibody detects endogenous levels of v-SNARE Vti1p protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human v-SNARE Vti1p.

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for VTI1B

Target: VTI1B (Vesicle Transport through Interaction with T-SNAREs Homolog 1B (VTI1B))

Alternative Name: v-SNARE Vti1p

Background:

Synonyms: VTI1B, VTI1, VTI1L, VTI1L1, VTI2, Vesicle transport through interaction with t-SNAREs homolog 1B, Vesicle transport v-SNARE protein Vti1-like 1, Vti1-rp1

Background: function:V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.,similarity:Belongs to the VTI1 family.,subunit:Found in a complex with VAMP8 and STX7 in the liver. Forms a SNARE complex with STX7, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Part of the SNARE core complex containing STX7, STX8 and VAMP8.,tissue specificity:Expressed in all tissues examined.,

Gene Name: VTI1B

Protein Name: Vesicle transport through interaction with t-SNAREs homolog 1B

Gene ID: 10490

UniProt: Q9UEU0