WT1 antibody (AA 350-449)

Catalog No. ABIN8125746

The Mouse Monoclonal anti-WT1 antibody is suitable to detect WT1 in samples from Human, Rat, Mouse and Pig. It has been validated for IHC.

Quick Overview for WT1 antibody (AA 350-449) (ABIN8125746)

Target: WT1 (Wilms Tumor 1 (WT1))

Reactivity: Human, Rat, Mouse, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This WT1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: AB1606

Product Details anti-WT1 Antibody

Binding Specificity: AA 350-449

Purpose: Wilms' Tumor 1 (WT1) Mouse mAb (Ready to Use)

Specificity: The antibody can specifically recognize human WT1 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 350 - 449 of the human Wilms' Tumor 1 protein.

Isotype: IgG

Application Details

Application Notes: It has been optimized for direct use, requiring no further dilution.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The ready - to - use antibody is provided in liquid form in phosphate buffer saline containing stabilizing protein and 0. 05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze

Storage: 4 °C

Storage Comment: Store at 4°C. Avoid freeze.

Target Details for WT1

Target: WT1 (Wilms Tumor 1 (WT1))

Alternative Name: Wilms' Tumor 1

Background:

Synonyms: WIT 2, WT 1, AWT1, FWT1, GUD, NPHS4, WAGR, Wilms tumor 1, Wilms Tumor, Wilms tumor protein, Wilms' tumor gene, Wilms' tumor protein, WIT2, WT, WT1, WT1_HUMAN, WT33

Background: WT1, located on chromosome 11p13, is a tumor suppressor gene, which mainly plays a role in the development of genitourinary organs. It was positive in ovarian serous carcinoma, peritoneal serous carcinoma, ovarian metastatic carcinoma, 50 % of ovarian endometrial carcinoma, posterior renal adenoma, most malignant mesothelioma and sex cord stromal tumor.

Gene Name: WT1

Protein Name: Wilms' Tumor 1

Gene ID: 7490

UniProt: P19544

Pathways: Tube Formation