WT1 antibody (AA 350-449)

Catalog No. ABIN8125748

This Mouse Monoclonal antibody specifically detects WT1 in IHC, WB, IF and ELISA. It exhibits reactivity toward Human, Rat, Mouse and Pig.

Quick Overview for WT1 antibody (AA 350-449) (ABIN8125748)

Target: WT1 (Wilms Tumor 1 (WT1))

Reactivity: Human, Rat, Mouse, Pig

Host: Mouse

Clonality: Monoclonal

Conjugate: This WT1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), ELISA

Clone: AB1606

Product Details anti-WT1 Antibody

Binding Specificity: AA 350-449

Purpose: Wilms' Tumor 1 (WT1) mouse mAb

Specificity: The antibody can specifically recognize human WT1 protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogen: A synthetic peptide corresponding to the amino acid region 350 - 449 of the human Wilms' Tumor 1 protein.

Isotype: IgG

Application Details

Application Notes: IHC, 1:200-1:1000 | WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at-20°C. Avoid freeze / thaw cycles.

Target Details for WT1

Target: WT1 (Wilms Tumor 1 (WT1))

Alternative Name: Wilms' Tumor 1

Background:

Synonyms: WIT 2, WT 1, AWT1, FWT1, GUD, NPHS4, WAGR, Wilms tumor 1, Wilms Tumor, Wilms tumor protein, Wilms' tumor gene, Wilms' tumor protein, WIT2, WT, WT1, WT1_HUMAN, WT33

Background: WT1, located on chromosome 11p13, is a tumor suppressor gene, which mainly plays a role in the development of genitourinary organs. It was positive in ovarian serous carcinoma, peritoneal serous carcinoma, ovarian metastatic carcinoma, 50 % of ovarian endometrial carcinoma, posterior renal adenoma, most malignant mesothelioma and sex cord stromal tumor.

Gene Name: WT1

Protein Name: Wilms' Tumor 1 (WT1)

Gene ID: 7490

UniProt: P19544

Pathways: Tube Formation