YBX1 antibody (pSer102)

Catalog No. ABIN8125781

This Rabbit Polyclonal antibody specifically detects YBX1 in WB. It exhibits reactivity toward Human and Mouse.

Quick Overview for YBX1 antibody (pSer102) (ABIN8125781)

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YBX1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-YBX1 Antibody

Binding Specificity: pSer102

Purpose: YB1 (Phospho Ser102) Antibody

Specificity: This antibody detects endogenous levels of Human Mouse YB1 (phospho-Ser102)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen: Synthesized phosho peptide around human YB1 (Ser102)

Isotype: IgG

Application Details

Application Notes: WB 1:1000-2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for YBX1

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Alternative Name: YB1

Background:

Synonyms: Tryptase alpha/beta-1 (Tryptase-1) (EC 3.4.21.59) (Tryptase I) (Tryptase alpha-1)

Background: Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate gene

Gene Name: TPSAB1 TPS1 TPS2 TPSB1

Protein Name: YB1 (Ser102)

Gene ID: 7177

UniProt: Q15661

Pathways: Regulation of Muscle Cell Differentiation