GLI1 antibody (AA 460-490)

Catalog No. ABIN8125822

The Rabbit Polyclonal anti-GLI1 antibody (ABIN8125822) specifically detects GLI1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for GLI1 antibody (AA 460-490) (ABIN8125822)

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLI1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GLI1 Antibody

Binding Specificity: AA 460-490

Purpose: GLI-1 Antibody

Specificity: This antibody detects endogenous levels of GLI-1

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human GLI-1. at AA range: 460-490

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000, ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GLI1

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Alternative Name: GLI-1

Background:

Synonyms: Zinc finger protein GLI1 (Glioma-associated oncogene) (Oncogene GLI)

Background: This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],

Gene Name: GLI1 GLI

Protein Name: GLI-1

Gene ID: 2735

UniProt: P08151

Pathways: Hedgehog Signaling, Dopaminergic Neurogenesis