ST5 antibody (AA 1051-1137)

Catalog No. ABIN762611

Product Details anti-ST5 Antibody

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Binding Specificity: AA 1051-1137

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ST5 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ST5/DENND2B

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ST5

Target: ST5 (Suppression of Tumorigenicity 5 (ST5))

Alternative Name: St5 (ST5 Products)

Synonyms: zgc:91902 antibody, wu:fc11b09 antibody, si:ch211-208c6.1 antibody, ST5 antibody, DKFZp459D1230 antibody, hts1 antibody, p126 antibody, dennd2b antibody, DENND2B antibody, HTS1 antibody, 2010004M01Rik antibody, 2610305K15Rik antibody, suppression of tumorigenicity 5 antibody, st5 antibody, ST5 antibody, St5 antibody

Background:

Synonyms: DENND2B, DENN domain containing protein 2B, HeLa tumor suppression 1, DENN domain-containing protein 2B, DENN/MADD domain containing 2B, DENND2B, HTS1, p126, ST 5, ST5, ST5_HUMAN, Suppression of tumorigenicity 5, Suppression of tumorigenicity 5 protein.

Background: This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified. [provided by RefSeq, Jul 2008].

Gene ID: 6764