CD90 antibody

Catalog No. ABIN775703

Product Details anti-CD90 Antibody

Target: CD90 (THY1)

Reactivity: Human, Pig, Horse, Non-Human Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD90 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Specificity: The mouse monoclonal antibody 5E10 recognizes CD90/Thy-1, a GPI-anchored cell surface glycoprotein expressed predominantly on thymocytes, hematopoietic stem cells and neurons.

No Cross-Reactivity: Dog

Cross-Reactivity (Details): Human, Non-Human Primates, Porcine, Equine (Horse)

Purification: Purified by protein-A affinity chromatography.

Purity: > 95 % (by SDS-PAGE)

Immunogen: HEL erythroleukemia cells

Clone: 5E10

Isotype: IgG1 kappa

Application Details

Application Notes: Flow cytometry: Recommended dilution: 1-3 μg/mL.
Immunohistochemistry: Recommended dilution: 5-10 μg/mL.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Preservative: Azide free

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

References for anti-CD90 antibody (ABIN775703)

Hoppstädter, Diesel, Zarbock, Breinig, Monz, Koch, Meyerhans, Gortner, Lehr, Huwer, Kiemer: "Differential cell reaction upon Toll-like receptor 4 and 9 activation in human alveolar and lung interstitial macrophages." in: Respiratory research, Vol. 11, pp. 124, (2010) (PubMed).

Kroeze, Jurgens, Doulabi, van Milligen, Scheper, Gibbs: "Chemokine-mediated migration of skin-derived stem cells: predominant role for CCL5/RANTES." in: The Journal of investigative dermatology, Vol. 129, Issue 6, pp. 1569-81, (2009) (PubMed).

Carlsten, Björkström, Norell, Bryceson, van Hall, Baumann, Hanson, Schedvins, Kiessling, Ljunggren, Malmberg: "DNAX accessory molecule-1 mediated recognition of freshly isolated ovarian carcinoma by resting natural killer cells." in: Cancer research, Vol. 67, Issue 3, pp. 1317-25, (2007) (PubMed).

Seiffert, Brossart, Cant, Cella, Colonna, Brugger, Kanz, Ullrich, Bühring: "Signal-regulatory protein alpha (SIRPalpha) but not SIRPbeta is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34(+)CD38(-) hematopoietic cells." in: Blood, Vol. 97, Issue 9, pp. 2741-9, (2001) (PubMed).

Ito, Inaba, Inaba, Toki, Sogo, Iguchi, Adachi, Yamaguchi, Amakawa, Valladeau, Saeland, Fukuhara, Ikehara: "A CD1a+/CD11c+ subset of human blood dendritic cells is a direct precursor of Langerhans cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 3, pp. 1409-19, (1999) (PubMed).

Target Details for CD90

Target: CD90 (THY1)

Alternative Name: CD90 (THY1 Products)

Synonyms: CD90 antibody, CD7 antibody, T25 antibody, Thy-1 antibody, Thy-1.2 antibody, Thy1.1 antibody, Thy1.2 antibody, Thy-1 cell surface antigen antibody, thymus cell antigen 1, theta antibody, THY1 antibody, Thy1 antibody

Background: Thy-1 cell surface antigen,CD90 (Thy-1) is an 18-35 kDa GPI-anchored plasma membrane glycoprotein expressed in many cell types, such as in hematopoietic cells and neurons, connective tissues, various fibroblast and stromal cell lines, tumor endothelial cell lines and other. It is involved in T cell activation, cellular adhesion, proliferation and migration, neurite outgrowth, wound healing, apoptosis, and fibrosis. CD90 participates in multiple signaling cascades and its effects are tissue- and cell type-specific. It often functions as an important regulator of cell-cell and cell-matrix interactions.,Thy-1

Gene ID: 7070

UniProt: P04216

Pathways: Cell-Cell Junction Organization