HSP70 1A antibody

Catalog No. ABIN781228

The Mouse Monoclonal anti-HSP70 1A antibody (ABIN781228) specifically detects HSP70 1A in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for HSP70 1A antibody (ABIN781228)

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSP70 1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HSP70 1A Antibody

Specificity: Cytoplasm

Purification: Protein G-Sepharose affinity purified.

Immunogen: Recombinant fragment of human HSPA1A (C-terminus).

Isotype: IgG

Application Details

Application Notes: Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 50µg/50µl

Buffer: 0.02% Sodium Azide and 50% glycerol, 1%BSA, PBS, pH7.4.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for HSP70 1A

Target: HSP70 1A (HSPA1A) (Heat Shock 70kDa Protein 1A (HSPA1A))

Alternative Name: HSPA1A

Background: Hsp70 genes encode abundant heat-inducible 70-kDa hsps (hsp70s). In most eukaryotes hsp70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes show a high degree of conservation, having at least 5O% identity. The structure of this ATP binding domain displays multiple features of nucleotide binding proteins. The molecular chaperones of the hsp70 family recognize and bind to nascent polypeptide chains as well as partially folded intermediates of proteins preventing their aggregation and misfolding.

Molecular Weight: 70kDa

NCBI Accession: NM_005345

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process