L1CAM antibody

Catalog No. ABIN781316

This Mouse Monoclonal antibody specifically detects L1CAM in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for L1CAM antibody (ABIN781316)

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This L1CAM antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-L1CAM Antibody

Specificity: Plasma membrane

Purification: Protein G-Sepharose affinity purified

Immunogen: Recombinant fragment of Human L1CAM (C-terminus).

Isotype: IgG

Application Details

Application Notes: Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 50µg/50µl

Buffer: 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for L1CAM

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Alternative Name: L1CAM

Background: The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius), 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs), and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation.

Molecular Weight: 40kDa

NCBI Accession: NM_000425

Pathways: Synaptic Membrane