PIK3R1 antibody
Quick Overview for PIK3R1 antibody (ABIN781332)
Target
See all PIK3R1 (PI3K p85a) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Plasma membrane.
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Purification
- Protein G-Sepharose affinity purified.
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Immunogen
- Recombinant fragment of Human PIK3R1 (C- terminus).
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Isotype
- IgG
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Application Notes
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 50µg/50µl
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Buffer
- 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
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Alternative Name
- PIK3R1
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Background
- Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance.
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Molecular Weight
- 57kDa
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NCBI Accession
- NM_181523
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Pathways
- TCR Signaling, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effect
Target
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