SOX2 antibody
Quick Overview for SOX2 antibody (ABIN781337)
Target
See all SOX2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Specificity
- Nucleus
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Purification
- Protein G-Sepharose affinity purified.
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Immunogen
- Recombinant full length protein of mouse Sox2.
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Isotype
- IgG
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Application Notes
- Recommended dilutions. ELISA: 1/5000 - 1/20000. WB: 1/100-1/2000.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 50µg/50µl
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Buffer
- 0.02% Sodium Azide and 50% glycerol, 1% BSA, PBS, pH7.4.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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Alternative Name
- Sox2
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Background
- This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation.
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Molecular Weight
- 40kDa
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NCBI Accession
- NM_011443
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Pathways
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
Target
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