ADK antibody

Catalog No. ABIN781539

The Mouse Monoclonal anti-ADK antibody (Clone AT4F8) (ABIN781539) specifically detects ADK in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for ADK antibody (ABIN781539)

Target: ADK (Adenosine Kinase (ADK))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADK antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT4F8

Product Details anti-ADK Antibody

Specificity: The antibody recognizes human Adenosine kinase. Other species not tested.

Purification: Protein-G affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for ADK

Target: ADK (Adenosine Kinase (ADK))

Alternative Name: Adenosine Kinase (AK)

Background: Adenosine kinase (ADK) is the key regulator of adenosine metabolism. Because of the manifold receptor-dependent actions of adenosine, tight regulation of adenosine levels is crucial. The intracellular and extracellular pools of adenosine are in dynamic exchange by equilibrative and concentrative nucleoside transporters, so extracellular concentrations of adenosine are regulated by interplay of theses transporters with intracellular and extracellular enzymes of adenosine metabolism. Thus, the extracellular concentration of adenosine is enhanced by inhibition of equilibrative nucleoside transporters such as S-(4-nitrobenzyl)-6-thioinosine and cannabidiol and, stimulation of extracellular ATP breakdown and inhibition of intracellular adenosine removal.Synonyms: ADK, Adenosine 5'-phosphotransferase

Gene ID: 132

Pathways: Ribonucleoside Biosynthetic Process