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HCV NS5 antibody (AA 77-86)

HCV NS5 Reactivity: Human WB, EIA, IP Host: Mouse Monoclonal 6G5 unconjugated
Catalog No. ABIN781781
  • Target See all HCV NS5 products
    HCV NS5 (Hepatitis C Virus NS5 (HCV NS5))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 77-86
    Reactivity
    • 7
    • 3
    Human
    Host
    • 9
    • 1
    Mouse
    Clonality
    • 9
    • 1
    Monoclonal
    Conjugate
    • 10
    This HCV NS5 antibody is un-conjugated
    Application
    • 9
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunoprecipitation (IP)
    Purification
    Protein G Affinity chromatography
    Immunogen
    Recombinant Hepatitis C Virus nonstructural protein 5B (NS5B) RNAdependent RNA polymerase (RdRp)
    Clone
    6G5
    Isotype
    IgG1
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS pH 7.4, with 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Upon receipt, store (in aliquots) at -20 to -70 °C.
  • Nikonov, Juronen, Ustav: "Functional characterization of fingers subdomain-specific monoclonal antibodies inhibiting the hepatitis C virus RNA-dependent RNA polymerase." in: The Journal of biological chemistry, Vol. 283, Issue 35, pp. 24089-102, (2008) (PubMed).

  • Target
    HCV NS5 (Hepatitis C Virus NS5 (HCV NS5))
    Alternative Name
    HCV NS5 (HCV NS5 Products)
    Target Type
    Viral Protein
    Background
    Non-structural protein 5B (NS5B) represents the RNA-dependent RNA polymerase (RdRp) of Hepatitis C Virus, which is a small positive strand RNA virus in the family Flaviviridae. HCV is a major causative agent of acute and chronic hepatitis, hepatocellular carcinoma and liver cirrhosis. The single subunit RNA-dependent RNA polymerase is absolutely essential for the viral replication.Synonyms: Hepatitis C Virus, RNA-directed RNA polymerase NS5B
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