LI Cadherin antibody (AA 24-132)

Catalog No. ABIN782351

The Mouse Monoclonal anti-LI Cadherin antibody is suitable to detect LI Cadherin in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for LI Cadherin antibody (AA 24-132) (ABIN782351)

Target: LI Cadherin

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LI Cadherin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 3H2

Product Details anti-LI Cadherin Antibody

Binding Specificity: AA 24-132

Specificity: Recognizes Cadherin-17

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Protein A Chromatography

Immunogen: CDH17 antibody was raised against CDH17 (NP_004054, 24 a.a. ~ 132 a.a) partial recombinant protein with GST tag.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.2

Handling Advice: Avoid freeze-thaw cycles.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C or -80 °C.

Target Details for LI Cadherin

Target: LI Cadherin

Alternative Name: Cadherin-17

Background: The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including catenin beta, to regulate cadherin function. LI-cadherin (for liver-intestine-cadherin) expression is restricted to liver and intestine tissues and is specifically localized to the basolateral domain of hepatocytes and enterocytes.Synonyms: CDH17, HPT-1, HPT1, Intestinal peptide-associated transporter HPT-1, Liver-intestine cadherin

Gene ID: 1015

NCBI Accession: NP_001138135

UniProt: Q12864