MAG antibody (AA 119-209)

Catalog No. ABIN782426

The Mouse Monoclonal anti-MAG antibody is suitable to detect MAG in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for MAG antibody (AA 119-209) (ABIN782426)

Target: MAG (Myelin Associated Glycoprotein (MAG))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAG antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 3C7

Product Details anti-MAG Antibody

Binding Specificity: AA 119-209

Specificity: This antibody reacts to MAG.

Purification: Affinity chromatography on Protein A

Immunogen: MAG antibody was raised against mAG (NP_002352, 119 a.a. ~ 209 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0,24 mg/mL

Buffer: PBS, pH 7.2

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody at -20 °C to -80 °C.

Target Details for MAG

Target: MAG (Myelin Associated Glycoprotein (MAG))

Alternative Name: Myelin-Associated Glycoprotein (MAG)

Background: Myelin-associated glycoprotein (MAG), a member of the immunoglobulin superfamily, is a membrane glycoprotein of 100 kDa, and is thought to be involved in the process of myelination. Axonal regeneration in the adult central nervous system (CNS) is limited by two proteins in myelin, Nogo and MAG. MAG has been implicated in the inhibition of nerve regeneration in the CNS.Synonyms: GMA, MAG, Siglec-4a

Gene ID: 4099

NCBI Accession: NP_002352

UniProt: P20916

Pathways: Neurotrophin Signaling Pathway