Glutamate Receptor 1 antibody (N-Term)

Catalog No. ABIN782441

The Mouse Monoclonal anti-Glutamate Receptor 1 antibody is suitable to detect Glutamate Receptor 1 in samples from Rat and Mouse. It has been validated for WB.

Quick Overview for Glutamate Receptor 1 antibody (N-Term) (ABIN782441)

Target: Glutamate Receptor 1 (GLUR1)

Reactivity: Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Glutamate Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RH95

Product Details anti-Glutamate Receptor 1 Antibody

Binding Specificity: N-Term

Specificity: Specific for the ~105k GluR1 protein.

Cross-Reactivity (Details): Species reactivity (tested):Mouse and Rat.

Purification: Protein G Chromatography of Culture Supernatant

Immunogen: Peptide corresponding to amino acid residues from the N-terminal region of Rat GluR1.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted (in aliquots) at -20 °C.

Target Details for Glutamate Receptor 1

Target: Glutamate Receptor 1 (GLUR1)

Alternative Name: Glutamate Receptor 1 / GLUR1

Background: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990, Hollmann and Heinemann, 1994).Synonyms: AMPA-selective glutamate receptor 1, AMPA1, GLUH1, GRIA1, GluR-1, GluR-A, GluR-K1, Glutamate receptor ionotropic

Gene ID: 50592

NCBI Accession: NP_113796

UniProt: P19490

Pathways: PI3K-Akt Signaling