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PNPO antibody (AA 57-261)
PNPO
Reactivity: Human
WB, EIA
Host: Mouse
Monoclonal
AT2C7
unconjugated
Product Details anti-PNPO Antibody
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Target
See all PNPO Antibodies
PNPO
(Pyridoxamine 5'-Phosphate Oxidase (PNPO))
Binding Specificity
All epitopes for PNPO antibodies
AA 57-261
Reactivity
All reactivities for PNPO antibodies
Human
Host
All hosts for PNPO antibodies
Mouse
Clonality
All clonalities for PNPO antibodies
Monoclonal
Conjugate
All conjugates for PNPO antibodies
This PNPO antibody is un-conjugated
Application
All applications for PNPO antibodies
Western Blotting (WB), Enzyme Immunoassay (EIA)
Specificity
Teh antibody recognizes human PNPO. Other species not tested.
Purification
Protein-G affinity chromatography
Immunogen
Recombinant human PNPO (57-261aa) purified from E. coli
Clone
AT2C7
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.0 mg/mL
Buffer
PBS, pH 7.4, containing 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for PNPO
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Target
PNPO
(Pyridoxamine 5'-Phosphate Oxidase (PNPO))
Alternative Name
PNPO (PNPO Products )
Synonyms
im:7138360 antibody, ECK1634 antibody, JW1630 antibody, PDXPO antibody, AI415282 antibody, pyridoxamine 5'-phosphate oxidase antibody, pyridoxine 5'-phosphate oxidase antibody, Pyridoxamine 5'-phosphate oxidase antibody, pnpo antibody, pdxH antibody, Mrub_2888 antibody, Arnit_1624 antibody, Ndas_4168 antibody, Mesil_2817 antibody, Isop_0296 antibody, Despr_1960 antibody, Pedsa_1348 antibody, Mesop_5639 antibody, PNPO antibody, Pnpo antibody
Background
PNPO (pyridoxamine 5'-phosphate oxidase) is a 261 amino acid protein belonging to the pyridoxamine 5'-phosphate oxidase family. It is the rate-limiting enzyme in vitamin B6 synthesis. Vitamin B6 (Pyridoxal 5-prime-phosphate or PLP) is vital for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.Synonyms: Pyridoxamine-phosphate oxidase, Pyridoxine-5'-phosphate oxidase
Gene ID
55163
NCBI Accession
NP_060599
UniProt
Q9NVS9
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