FBXL3 antibody (N-Term)
Quick Overview for FBXL3 antibody (N-Term) (ABIN783328)
Target
See all FBXL3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-5, N-Term
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Sequence
- M-K-R-G-G
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Specificity
- This antibody detects endogenous levels of total FBXL3 protein.
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Cross-Reactivity (Details)
- Species reactivity (tested):Mouse
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Purification
- Affinity-chromatography using epitope-specific peptide
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Immunogen
- Peptide sequence around aa.1~5 derived from mouse FBXL3
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store (in aliquots) at -20 °C.
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- FBXL3 (F-Box and Leucine-Rich Repeat Protein 3 (FBXL3))
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Alternative Name
- FBXL3
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Background
- This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats and is localized in the nucleus.Synonyms: F-box and leucine-rich repeat protein 3A, F-box/LRR-repeat protein 3, F-box/LRR-repeat protein 3A, FBL3A, FBXL3A
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Molecular Weight
- 49 kDa
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Gene ID
- 50789
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NCBI Accession
- NP_056637
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UniProt
- Q8C4V4
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Pathways
- Photoperiodism
Target
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