ZMYM3 antibody (N-Term)
Quick Overview for ZMYM3 antibody (N-Term) (ABIN783369)
Target
See all ZMYM3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Specificity
- This antibody detects ZMYM3 at N-term. At least three isoforms of ZMYM3 are known to exist, this antibody will detect all three. ZMYM3 antibody is predicted to not cross-react with other ZMYM protein family members.
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Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse
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Purification
- Affinity chromatography purified via peptide column
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Immunogen
- 20 amino acid peptide near the amino terminus of human AXIN2
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Buffer
- PBS containing 0.02 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- ZMYM3 (Zinc Finger Protein 261 (ZMYM3))
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Alternative Name
- ZMYM3
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Background
- Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM3 is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X,13) involving this gene is associated with X-linked mental retardation.Synonyms: DXS6673E, KIAA0385, ZNF261, Zinc finger MYM-type protein 3, Zinc finger protein 261
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Gene ID
- 9203
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NCBI Accession
- NP_001164633
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UniProt
- Q14202
Target
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