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ZNF219 antibody (N-Term)

ZNF219 Reactivity: Human, Mouse, Rat WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783427
  • Target See all ZNF219 Antibodies
    ZNF219 (Zinc Finger Protein 219 (ZNF219))
    Binding Specificity
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 10
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 10
    Rabbit
    Clonality
    • 10
    Polyclonal
    Conjugate
    • 10
    This ZNF219 antibody is un-conjugated
    Application
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects ZNF219 at N-term. At least two isoforms of ZFP219 are known to exist, this antibody will recognize both.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human, mouse, rat
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    18 amino acid peptide near the amino terminus of human ZFP219
    Top Product
    Discover our top product ZNF219 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    ZNF219 (Zinc Finger Protein 219 (ZNF219))
    Alternative Name
    ZNF219 (ZNF219 Products)
    Synonyms
    ZNF219 antibody, ZFP219 antibody, Znf219 antibody, 2010302A17Rik antibody, zinc finger protein 219 antibody, ZNF219 antibody, Zfp219 antibody
    Background
    ZFP219 is a developmentally regulated member of the Kruppel-like zinc finger gene family that is thought to function as a transcriptional repressor. Yeast two-hybrid screening showed association with Sox9, a transcription factor that is essential for chondrogenesis. ZFP219 is specifically expressed in the developing limb buds and colocalizes with Sox9 in the nucleus. Knockdown of ZFP219 expression decreased Sox9-induced mRNA expression, and a dominant-negative mutant of ZFP219 inhibited Bmp2-induced chondrocyte differentiation, suggesting that ZFP219 plays an important role as a transcriptional partner of Sox9 in the regulation of chondrocyte differentiation.Synonyms: Zinc finger protein 219
    Gene ID
    51222
    NCBI Accession
    NP_001095142
    UniProt
    Q9P2Y4
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