SH3RF2 antibody (C-Term)

Catalog No. ABIN783691

This Rabbit Polyclonal antibody specifically detects SH3RF2 in WB and EIA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for SH3RF2 antibody (C-Term) (ABIN783691)

Target: SH3RF2 (SH3 Domain Containing Ring Finger 2 (SH3RF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SH3RF2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SH3RF2 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects SH3RF2 / RNF158 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the carboxy terminus of human SH3RF2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for SH3RF2

Target: SH3RF2 (SH3 Domain Containing Ring Finger 2 (SH3RF2))

Alternative Name: SH3RF2 / RNF158

Background: Although the SH3 domain containing ring finger 2 protein (SH3RF2) has been identified as a marker of the nucleus accumbens in the human brain, little is known about this protein. Recent yeast two-hybrid experiments have shown that SH3RF2 associates with protein phosphatase 1 (PP1) and is expressed primarily in heart and testis tissue. Recombinant SH3RF2 enhanced PP1 enzymatic activity and antagonized the ability of phopho-inhibitor-1 or -2 to inhibit PP1, suggesting that SH3RF2 may play a role working with PP1 in cardiac functions.Synonyms: Putative E3 ubiquitin-protein ligase SH3RF2, RING finger protein 158, SH3 domain-containing RING finger protein 2

Gene ID: 153769

NCBI Accession: NP_689763

UniProt: Q8TEC5