TCF12 antibody (N-Term)

Catalog No. ABIN783743

The Rabbit Polyclonal anti-TCF12 antibody is suitable to detect TCF12 in samples from Human, Rat and Mouse. It has been validated for WB and EIA.

Quick Overview for TCF12 antibody (N-Term) (ABIN783743)

Target: TCF12 (Transcription Factor 12 (TCF12))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCF12 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-TCF12 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects TCF12 at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the amino terminus of human TCF12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for TCF12

Target: TCF12 (Transcription Factor 12 (TCF12))

Alternative Name: TCF12

Background: TCF12, also known as HTF4, is a member of the basic helix-loop-helix (bHLH) E-protein family that recognizes the consensus binding site (E-box) CANNTG. TCF12 is expressed in many tissues, among them skeletal muscle, thymus, B- and T-cells, and may participate in regulating lineage-specific gene expression through the formation of heterodimers with other bHLH E-proteins. TCF12, in combination with E2A, is required to block thymocyte proliferation prior to pre-TCR expression and is critical for proper T cell differentiation. Recent reports have shown that TCF12 is also a critical factor required for the development of invariant natural killer T cells.Synonyms: DNA-binding protein HTF4, E-box-binding protein, HEB, HTF-4, HTF4, Transcription factor 12, Transcription factor HTF-4

Gene ID: 6938

NCBI Accession: NP_003196

UniProt: Q99081

Pathways: SARS-CoV-2 Protein Interactome