PEAR1 antibody (C-Term)

Catalog No. ABIN783779

The Rabbit Polyclonal anti-PEAR1 antibody is suitable to detect PEAR1 in samples from Human, Mouse and Rat. It has been validated for WB and EIA.

Quick Overview for PEAR1 antibody (C-Term) (ABIN783779)

Target: PEAR1 (Platelet Endothelial Aggregation Receptor 1 (PEAR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEAR1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PEAR1 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects PEAR1 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of human PEAR1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for PEAR1

Target: PEAR1 (Platelet Endothelial Aggregation Receptor 1 (PEAR1))

Alternative Name: PEAR1

Background: Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated, the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbb3 antagonist that also inhibits platelet aggregation. Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.Synonyms: MEGF12, Multiple EGF-like domains protein 12, Multiple epidermal growth factor-like domains protein 12, Platelet endothelial aggregation receptor 1

Gene ID: 375033

NCBI Accession: NP_001073940

UniProt: Q5VY43