CDC23 antibody (Center)
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- Target See all CDC23 Antibodies
- CDC23 (Cell Division Cycle 23 (CDC23))
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Binding Specificity
- Center
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CDC23 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, mouse, rat
- Purification
- Affinity chromatography purified via peptide column
- Immunogen
- 17 amino acid peptide near the center of human APC8
- Top Product
- Discover our top product CDC23 Primary Antibody
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anti-Cell Division Cycle 23 (CDC23) (AA 366-597) antibody
CDC23 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (AA 50-150) antibodyCDC23 Reactivity: Human WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) antibodyCDC23 Reactivity: Human, Mouse, Rat IHC Host: Rabbit Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (AA 491-591) antibodyCDC23 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 1F3 unconjugated
anti-Cell Division Cycle 23 (CDC23) (Internal Region) antibodyCDC23 Reactivity: Human, Mouse, Monkey WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (Internal Region) antibodyCDC23 Reactivity: Human, Mouse WB, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (AA 140-168), (N-Term) antibodyCDC23 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB19769 unconjugated
anti-Cell Division Cycle 23 (CDC23) antibodyCDC23 Reactivity: Human WB, IF Host: Rabbit Monoclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (AA 62-142) antibodyCDC23 Reactivity: Human ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (AA 101-150) antibodyCDC23 Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Monkey, Xenopus laevis, Chicken, Zebrafish (Danio rerio), Bat, Pig WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- PBS containing 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store the antibody (in aliquots) at -20 °C.
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- Target
- CDC23 (Cell Division Cycle 23 (CDC23))
- Alternative Name
- CDC23 / APC8 (CDC23 Products)
- Background
- Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC8 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. In Drosophila, silencing of APC8 results in developmental delay and pupal lethality with elevated levels of apoptosis, high mitotic index, and delayed or blocked mitosis.Synonyms: ANAPC8, Anaphase-promoting complex subunit 8, Cell division cycle protein 23 homolog, Cyclosome subunit 8
- Gene ID
- 8697
- NCBI Accession
- NP_004652
- UniProt
- Q9UJX2
- Pathways
- Protein targeting to Nucleus
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