ANAPC13 antibody (Center)

Catalog No. ABIN783826

This Rabbit Polyclonal antibody specifically detects ANAPC13 in WB and EIA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ANAPC13 antibody (Center) (ABIN783826)

Target: ANAPC13 (Anaphase Promoting Complex Subunit 13 (ANAPC13))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANAPC13 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ANAPC13 Antibody

Binding Specificity: Center

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the center of human APC13

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for ANAPC13

Target: ANAPC13 (Anaphase Promoting Complex Subunit 13 (ANAPC13))

Alternative Name: ANAPC13

Background: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC13 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. APC13 promotes the stable association of APC3/Cdc27 and APC6/Cdc16 with the APC/C.Synonyms: Anaphase-promoting complex subunit 13, Cylosome subunit 13

Gene ID: 25847

NCBI Accession: NP_056206

UniProt: Q9BS18