Transmembrane Protein 18 (TMM18) (C-Term) antibody
-
- Target See all Transmembrane Protein 18 (TMM18) Antibodies
- Transmembrane Protein 18 (TMM18)
-
Binding Specificity
- C-Term
- Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- Un-conjugated
-
Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificity
- This antibody reacts to Transmembrane protein 18.
- Purification
- Affinity chromatography
- Immunogen
- 15 amino acid peptide near the carboxy terminus of human TMEM18.
- Top Product
- Discover our top product TMM18 Primary Antibody
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Buffer
- PBS containing 0.02 % sodium azide as preservative
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C.
-
- Target
- Transmembrane Protein 18 (TMM18)
- Alternative Name
- TMEM18 (TMM18 Products)
- Synonyms
- BC024093 antibody, transmembrane protein 18 antibody, transmembrane protein 18 L homeolog antibody, TMEM18 antibody, Tmem18 antibody, tmem18.L antibody
- Background
- Recent studies have examined how overexpression of certain genes enhances the tropism of neural stem cells (NSCs) for gliomas. Overexpression of Transmembrane protein 18 (TMEM18) provides NSCs and neural precursors an increased migration capacity towards glioblastoma cells in vitro and in the rat brain, while functional inactivation of the gene resulted in an almost complete loss of migration activity, suggesting that TMEM18 could be a potential target in NSC-based glioma therapy. Other recent results suggest that among others, the TMEM18 loci is associated with higher than normal body mass index (BMI) and obesity, indicating there may be a CNS-related role in predisposition to obesity. Multiple isoforms of TMEM18 are known to exist.Synonyms: Transmembrane protein 18
- Gene ID
- 129787
- NCBI Accession
- NP_690047
- UniProt
- Q96B42
-