LY75/DEC-205 antibody (N-Term)

Catalog No. ABIN783835

This Chicken Polyclonal antibody specifically detects LY75/DEC-205 in IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for LY75/DEC-205 antibody (N-Term) (ABIN783835)

Target: LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

Reactivity: Human

Host: Chicken

Clonality: Polyclonal

Conjugate: This LY75/DEC-205 antibody is un-conjugated

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-LY75/DEC-205 Antibody

Binding Specificity: N-Term

Specificity: This antibody detects CD205.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography

Immunogen: Synthetic peptide coupled to carreir protein. The antibody was made against a central part of the Ricin B-type lectin, a domain located in the N-terminal extracellular portion of the DEC-205 protein.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Reconstitute by adding 0.5 mL distilled water.

Buffer: Stock solution contains 0.4 mg/mL IgY, phosphate buffered saline pH 7.2 (PBS), 5 mg/mL bovine serum albumin (BSA) as a stabilizer and 0.01 % Kathon as a preservative.

Preservative: Kathon CG

Precaution of Use: This product contains Kathon CG a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store (in aliquots) at -20 °C.

Target Details for LY75/DEC-205

Target: LY75/DEC-205 (LY75) (Lymphocyte Antigen 75 (LY75))

Alternative Name: CD205 / DEC-205

Background: Type I cell surface protein is expressed primarily by dendritic cells (DC). It is found on interdigitating dendritic cells in T-cell areas of lymphoid tissues, bone marrow-derived DC, Langerhans cells and at low levels on macrophages and T-cells. Tissue distribution of DEC-205 is comparable between human and mouse.Synonyms: C-type lectin domain family 13 member B, CLEC13B, DEC205, LY75, Lymphocyte antigen 75, gp200-MR6

Gene ID: 100526664

NCBI Accession: NP_001185688

UniProt: O60449