CCR4 antibody

Catalog No. ABIN783858

The Rabbit Polyclonal anti-CCR4 antibody (ABIN783858) specifically detects CCR4 in WB. The antibody is reactive with Human, Mouse and Dog samples.

Quick Overview for CCR4 antibody (ABIN783858)

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Reactivity: Human, Mouse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCR4 Antibody

Specificity: This antibody detects CCR4 surrounding amino acid 32.

Cross-Reactivity (Details): Species reactivity (tested):Human, mouse, dog

Purification: Affinity chromatography

Immunogen: Synthetic peptide surrounding amino acid 32 of human CCR4

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered saline (PBS) containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C.

Target Details for CCR4

Target: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Alternative Name: CD194 / CCR4

Background: CCR4 is a chemokine receptor and is preferentially expressed on type 2 helper T (Th2-type) cells. In contrast to other chemokine receptors, the expression of CCR4 and CCR8 on Th2 cells is transiently increased following TCR and CD28 engagement. Moreover, activated Th1 cells up-regulate CCR4 expression and functional responsiveness to thymus- and activation-regulated chemokine.Synonyms: C-C CKR-4, C-C chemokine receptor type 4, CC-CKR-4, CCR-4, CMKBR4, K5-5

Gene ID: 1233

NCBI Accession: NP_005499

UniProt: P51679