TXNDC11 antibody (Internal Region)

Catalog No. ABIN783977

The Goat Polyclonal anti-TXNDC11 antibody is suitable to detect TXNDC11 in samples from Human. It has been validated for WB and EIA.

Quick Overview for TXNDC11 antibody (Internal Region) (ABIN783977)

Target: TXNDC11 (Thioredoxin Domain Containing 11 (TXNDC11))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This TXNDC11 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-TXNDC11 Antibody

Binding Specificity: AA 113-126, Internal Region

Sequence: C-QLDYAEYVRR DSE

Specificity: Recognizes TXNDC11 (113-126).

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_056998.4. Genename: TXNDC11

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for TXNDC11

Target: TXNDC11 (Thioredoxin Domain Containing 11 (TXNDC11))

Alternative Name: TXNDC11

Background: TXNDC11 May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation. Belongs to the protein disulfide isomerase family. Interacts with the cytoplasmic part of DUOX1 and DUOX2. Interacts with TPO and CYBA. 3 isoforms of the human protein are produced by alternative splicing.Synonyms: EF-hand-binding protein 1, EFP1, Thioredoxin domain-containing protein 11

Gene ID: 51061

NCBI Accession: NP_056998

Pathways: Cell RedoxHomeostasis