The Goat Polyclonal anti-FZD9 antibody (ABIN783981) specifically detects FZD9 in IHC (p) and EIA.
The antibody is reactive with Human, Mouse and Rat samples.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
Tris saline, pH ~7.3 with 0.02 % Sodium Azide and 0.5 % BSA
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
FZD9
(Frizzled Family Receptor 9 (FZD9))
Alternative Name
CD349 / FZD9 / Frizzled-9
Background
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The Frizzled 9 gene is located within the Williams syndrome common deletion region of chromosome 7. Frizzled 9 is critical for hippocampal development and is likely to be a contributing factor to the neurodevelopmental and behavioral phenotype of patients with Williams syndrome. Expressed predominantly in adult and fetal brain, testis, eye, skeletal muscle and kidney. Moderately expressed in pancreas, thyroid, adrenal cortex, small intestine and stomach. Detected in fetal liver and kidney.Synonyms: Fz-9, hFz9