SLC1A5 antibody (Internal Region)

Catalog No. ABIN784185

Product Details anti-SLC1A5 Antibody

Target: SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))

Binding Specificity: Internal Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC1A5 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Human SLC1A5

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide - KLH conjugated corresponding to internal domain of Human SLC1A5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for SLC1A5

Target: SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))

Alternative Name: SLC1A5 (SLC1A5 Products)

Synonyms: aaat antibody, asct2 antibody, atbo antibody, m7v1 antibody, m7vs1 antibody, r16 antibody, rdrc antibody, AAAT antibody, ASCT2 antibody, ATBO antibody, M7V1 antibody, M7VS1 antibody, R16 antibody, RDRC antibody, Slc1a7 antibody, Asct2 antibody, H4-ASCT2 antibody, solute carrier family 1 (neutral amino acid transporter), member 5 antibody, solute carrier family 1 member 5 S homeolog antibody, solute carrier family 1 member 5 antibody, slc1a5 antibody, slc1a5.S antibody, SLC1A5 antibody, Slc1a5 antibody

Background: Solute Carrier Family 1 Member 5 (Slc1a5/ASCT2) belongs to a family of sodium dependent amino acid transporters. Slc1a5 has a preference for transporting zwitter ions. Slc1a5 also functions as a cell surface receptor for endogenously inherited retroviruses of cats, baboons and humans as well as for horizontally transmitted type-D simian retroviruses. In addition, it has been associated with increased metabolism in malignant tumors. In prostate carcinoma ASCT2 positivity is correlated with more aggressive biological behavior.Synonyms: ASCT2, ATB(0), Baboon M7 virus receptor, M7V1, Neutral amino acid transporter B(0), RD114/simian type D retrovirus receptor, RDR, RDRC, Sodium-dependent neutral amino acid transporter type 2, Solute carrier family 1 member 5

Gene ID: 6510

NCBI Accession: NP_005619

Pathways: Dicarboxylic Acid Transport, Warburg Effect