Serotonin Receptor 1A antibody (Internal Region)

Catalog No. ABIN784280

The Goat Polyclonal anti-Serotonin Receptor 1A antibody is suitable to detect Serotonin Receptor 1A in samples from Human, Rat and Mouse. It has been validated for WB and EIA.

Quick Overview for Serotonin Receptor 1A antibody (Internal Region) (ABIN784280)

Target: Serotonin Receptor 1A (HTR1A)

Reactivity: Human, Rat, Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This Serotonin Receptor 1A antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Serotonin Receptor 1A Antibody

Binding Specificity: Internal Region

Sequence: C-ERKNERTAEA KRK

Specificity: Recognizes Htr1a.

Cross-Reactivity (Details): Species reactivity (expected):Human, Rat.
Species reactivity (tested):Mouse.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_032334.2. Genename: Htr1a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Serotonin Receptor 1A

Target: Serotonin Receptor 1A (HTR1A)

Background: Serotonin receptor 1A belongs to the G-protein coupled receptor 1 family. 5-hydroxytryptamine receptor subfamily. HTR1A sub-subfamily. HTR1A is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.Synonyms: 5-HT-1A, 5-HT1A, 5-hydroxytryptamine receptor 1A, ADRB2RL1, ADRBRL1

NCBI Accession: NP_032334

Pathways: JAK-STAT Signaling, Synaptic Membrane, Feeding Behaviour