PPY antibody (Internal Region)

Catalog No. ABIN784304

Product Details anti-PPY Antibody

Target: PPY (Pancreatic Polypeptide (PPY))

Binding Specificity: Internal Region

Reactivity: Human, Rat, Mouse, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This PPY antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Sequence: C-TRPRYGKRHK EDT Remarks: Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Monkey (100%), Elephant (92%), Horse (92%), Marmoset (85%), Rat (85%), Sheep (85%), Bovine (85%).

Specificity: This antibody detects the internal region of PPY.

Cross-Reactivity (Details): Species reactivity (expected):Canine (Dog), Mouse and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic peptide from the internal region of of Human PPY (NP_002713.1).

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH ~7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-PPY antibody (ABIN784304)

Nakajima, Nishitsuji, Kawashima, Kuwabara, Mikawa, Uchimura, Akaji, Kashiwada, Kobayashi, Saito, Sakashita: "The polyphenol (-)-epigallocatechin-3-gallate prevents apoA-IIowa amyloidosis in vitro and protects human embryonic kidney 293 cells against amyloid cytotoxicity." in: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, Vol. 23, Issue 1, pp. 17-25, (2016) (PubMed).

Hong, Liu, Fan, Chen, Chen, Zheng, Zhang, Gao, Zhu: "New perspectives of vesicular monoamine transporter 2 chemical characteristics in mammals and its constant expression in type 1 diabetes rat models." in: Translational research : the journal of laboratory and clinical medicine, Vol. 163, Issue 2, pp. 171-82, (2014) (PubMed).

Wang, Liu, Liu, Dong, Glickman, Slaga, Zhou, Liu: "Up-regulation of adiponectin by resveratrol: the essential roles of the Akt/FOXO1 and AMP-activated protein kinase signaling pathways and DsbA-L." in: The Journal of biological chemistry, Vol. 286, Issue 1, pp. 60-6, (2011) (PubMed).

Target Details for PPY

Target: PPY (Pancreatic Polypeptide (PPY))

Alternative Name: Pancreatic Prohormone (PPY Products)

Synonyms: PPY antibody, PNP antibody, PP antibody, AV061413 antibody, IGSPP antibody, pancreatic polypeptide antibody, peptide YY antibody, PPY antibody, Ppy antibody, PYY antibody

Background: Synonyms: Obinepitide, PNP, PPY, Pancreatic polypeptide

Gene ID: 5539

NCBI Accession: NP_002713

Pathways: Feeding Behaviour