Huntingtin antibody (AA 2703-2911)

Catalog No. ABIN790678

This Mouse Monoclonal antibody specifically detects Huntingtin in IHC, WB, IP, IHC (p) and IHC (fro). It exhibits reactivity toward Human and Rabbit.

Quick Overview for Huntingtin antibody (AA 2703-2911) (ABIN790678)

Target: Huntingtin (HTT)

Reactivity: Human, Rabbit

Host: Mouse

Clonality: Monoclonal

Conjugate: This Huntingtin antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Huntingtin Antibody

Binding Specificity: AA 2703-2911

Specificity: Reacts with an epitope corresponding to the human HDC region (2703-2911 amino acids) of the huntingtin protein. Detects a 350kD band on Western Blots but also detects smaller degradation products of Huntingtin. Recognizes both denatured and native Huntingtin in human brain.

Purification: Protein G purified

Immunogen: Recombinant protein corresponding to amino acids 2703 - 2911 of huntingtin.

Type of Immunogen: Recombinant protein

Isotype: IgG1

Application Details

Application Notes: Approved: IHC, IHC-Fr, IHC-P (10 μg/mL), IP, WB

Usage: Suitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot. Immunohistochemistry: Frozen, FFPE (human). Increased cytoplasmic staining, relative to nuclear, has been reported using formaldehyde as a fixative compared with acetone/methanol. Positive control: IHC frozen-rabbit btain.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Huntingtin

Target: Huntingtin (HTT)

Alternative Name: HTT / Huntingtin

Background: Name/Gene ID: HTT
Family: Hungtintin

Synonyms: HTT, Huntingtin, Huntington disease protein, IT15, HD, HD protein

Gene ID: 3064

UniProt: P42858

Pathways: PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport