ECT2 antibody (pThr373) (FITC)

Catalog No. ABIN800695

This Rabbit Polyclonal antibody specifically detects ECT2 in WB, IF (cc) and IF (p). It exhibits reactivity toward Human.

Quick Overview for ECT2 antibody (pThr373) (FITC) (ABIN800695)

Target: ECT2 (Epithelial Cell Transforming Sequence 2 Oncogene (ECT2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ECT2 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-ECT2 Antibody (FITC)

Binding Specificity: pThr373

Predicted Reactivity: Human,Dog,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human ECT2 around the phosphorylation site of Thr373

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ECT2

Target: ECT2 (Epithelial Cell Transforming Sequence 2 Oncogene (ECT2))

Alternative Name: ECT2

Background:

Synonyms: ECT2 phospho T373, ECT2 phospho Thr373, p-ECT2 Thr373, ECT 2, ECT2, ECT-2, ECT2 protein, Epithelial cell transforming sequence 2, Epithelial cell transforming sequence 2 oncogene, Epithelial cell transforming sequence 2 oncogene protein, FLJ10461, MGC138291, Protein ECT2, ECT2_HUMAN, Epithelial cell-transforming sequence 2 oncogene.

Background: The protein encoded by this gene is a transforming protein that is related to Rho-specific exchange factors and yeast cell cycle regulators. The expression of this gene is elevated with the onset of DNA synthesis and remains elevated during G2 and M phases. In situ hybridization analysis showed that expression is at a high level in cells undergoing mitosis in regenerating liver. Thus, this protein is expressed in a cell cycle-dependent manner during liver regeneration, and is thought to have an important role in the regulation of cytokinesis. [provided by RefSeq].

Gene ID: 1894

Pathways: Neurotrophin Signaling Pathway, Cell-Cell Junction Organization