Integrin beta 3 antibody (pTyr785) (Cy3)

Catalog No. ABIN802281

This anti-Integrin beta 3 antibody is a Rabbit Polyclonal antibody detecting Integrin beta 3 in WB. Suitable for Human, Mouse and Rat.

Quick Overview for Integrin beta 3 antibody (pTyr785) (Cy3) (ABIN802281)

Target: Integrin beta 3 (ITGB3)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Integrin beta 3 antibody is conjugated to Cy3

Application: Western Blotting (WB)

Product Details anti-Integrin beta 3 Antibody (Cy3)

Binding Specificity: pTyr785

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human ITGB3 around the phosphorylation site of Tyr785

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Integrin beta 3

Target: Integrin beta 3 (ITGB3)

Alternative Name: Itgb3

Background:

Synonyms: Integrin beta chain, _3 precursor, Integrin Beta 3, CD 61, CD61, CD61 antigen, GP3A, GPIIIa, HPA 1, HPA 4, Integrin beta 3 platelet glycoprotein IIIa antigen CD61, Integrin beta chain beta 3, ITG B3, ITGB 3, ITGB3, NAIT, Platelet fibrinogen receptor beta subunit, Platelet glycoprotein IIIa, platelet glycoprotein IIIa precursor, Platelet membrane glycoprotein IIIa, PTP.

Background: The ITGB3 (Integrin beta chain beta 3) protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

Gene ID: 3690

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex