MUC1 antibody (C-Term)

Catalog No. ABIN870416

The Rabbit Monoclonal anti-MUC1 antibody has been validated for IHC (p). It is suitable to detect MUC1 in samples from Human.

Quick Overview for MUC1 antibody (C-Term) (ABIN870416)

Target: MUC1 (Mucin 1 (MUC1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MUC1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: G22-L

Product Details anti-MUC1 Antibody

Binding Specificity: AA 1235-1253, C-Term

Purpose: Anti-EMA (CD227, Mucin-1)

Specificity: EMA (CD227, Mucin

Immunogen: Peptide derived from C-terminal sequence of human Mucin-1. Antibody recognizes the epitope between Gly1235 - Ala1253.

Isotype: IgG

Application Details

Application Notes: IHC-P 1:100 - 200, IHC-Fr 1:400-600

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: +2 °C to +8 °C

Target Details for MUC1

Target: MUC1 (Mucin 1 (MUC1))

Alternative Name: EMA

Background: Anti-EMA antibody is a useful marker for staining several types of carcinomas. It stains normal and neoplastic cells from various tissues, including mammary epithelium, sweat glands and squamous epithelium. Hepatocellular carcinoma, adrenal carcinoma and embryonal carcinomas are consistently EMA negative, so keratin positivity with negative EMA favors one of these tumors. EMA is frequently positive in meningiomas, breast, ovary, lung and prostate tumors.

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling