ARNTL antibody (AA 569-573)

Catalog No. ABIN871641

The Rabbit Polyclonal anti-ARNTL antibody (ABIN871641) specifically detects ARNTL in WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for ARNTL antibody (AA 569-573) (ABIN871641)

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARNTL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARNTL Antibody

Binding Specificity: AA 569-573

Specificity: The antibody detects endogenous level of total BMAL1 protein.

Purification: Affinity purified

Immunogen: Peptide sequence around AA 569-573 (S-S-S-I-L) derived from Human BMAL1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Application Details

Application Notes: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for ARNTL

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Alternative Name: BMAL1

Background: ARNTL-CLOCK heterodimers activate E-box element (3'-CACGTG-5') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins

Molecular Weight: 69 kDa

Gene ID: 406

NCBI Accession: NP_001025

UniProt: O00327

Pathways: Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effect